Thursday, 28 May 2020

Crohn’s Disease Cured By Stem Cell Therapy

Updated: March 20, 2010 11:44 am

Stem cell transplant therapy has successfully cured patients suffering from Crohn’s disease, a terrible disease that afflicts an estimated 600,000 people in North America and millions more worldwide. Success in treating Crohn’s disease is just one of a string of recent success for stem cell and related therapies. The future for tens of millions of people suffering across the globe is looking brighter everyday as an explosion in treatments and cures for disease sees no signs of abating.

            Crohn’s disease is an autoimmune disease in which the body’s own immune system attacks the gastrointestinal tract, resulting in a lifetime of severe diarrhea and stomach pain for its sufferers. Severe is an understatement: for the worst sufferers Crohn’s disease can mean 20-30 painful and embarrassing diarrhea visits to the toilet everyday. Treatment is sometimes effective for mild cases of the disease, but for the most severe cases treatment options are very limited. Now with the recent development of a stem cell transplant cure, more than 20 individuals with the most severe form of the disease have seen their symptoms either completely or almost completely eradicated.

            The very first success in treating Crohn’s disease was performed on Joy Weiss eight years ago in 2001, and several other individuals have undergone the treatment since. In a recent press release from the Hospital Clinic in Spain, new information was released regarding the worldwide status of stem cell transplant treatments for Crohn’s. From the release we learn that the procedure has been performed on 12 patients in the US, 4 patients in Italy, and now 6 patients in Spain. Reportedly 80 per cent of the cases have witnessed total remission, and the remaining 20 per cent of cases have witnessed considerable improvement in quality of life.

            Given the success of the treatment one might be surprised to learn that only on the order of 20 individuals from a world population of millions of sufferers have undergone the treatment. The reality is that stem cell transplant therapy is a very serious procedure that patients choose to pursue only after careful consideration and after all other options have failed. Undergoing chemotherapy is no joke. It carries a small, yet unavoidable risk of cancer and is a serious drain on the patient’s body. Furthermore, replacing one’s entire immune system is a new and barely understood technique whose ramifications over the long term are still being studied. Although patients have now been in remission for up to seven or eight years and counting, it is yet to be seen how effective the therapy is 10 or 20 years down the road.

            Scottie Roy, a long time sufferer of Crohn’s disease has an excellent blog that catalogs his battle with the disease. As more research and data is accumulated, and as the technique is refined, stem cell transplant therapy will hopefully become an increasingly viable treatment for m0ore and more Chrohn’s sufferers.

By Saswat Mohapatra

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